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Laziness
Beginning of essay
Keratinization, absence of granular layer, and depositation of antibodies
and complement components in the stratum corneum. Most notable is the
hyperproliferation of keratinocytes in the epidermis. These keratinocytes
exhibit an increased mitotic rate and have ten times the turnover rate of
normal ....
Middle of essay
....igen in the context of MHC class II. These
activated T lymphocytes then migrate to the epidermis and activate
epidermal keratinocytes.
At this point, a cascade of events occurs and appears to become
cyclic after up-regulation of certain cytokines. This cyclic tendency is
probably responsible for the static nature of many psoriatic plaques. An
increase in ICAM-1 and ELAM-1 (endothelial leukocyte adhesion molecule) in
the vascular endothelium underlying the plaque recruits inflammator.... |
| Number of words: 1951 |
Approximate pages: 8 |
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