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Muscular Dystrophy
Beginning of essay
refers to, not one, but a group of muscle diseases. These diseases have three features in common: they are hereditary; they are progressive; and each causes a characteristic and selective pattern of weakness. Duchenne (DMD) is the most prevalent and severe childhood form of this group of diseas ....
Middle of essay
....either absent or severely deficient in a person with DMD. When dystrophin is lost through gene mutation, the muscle falls apart under the tension generated when it contracts. Without dystrophin, the muscle fibers also lose their ability to regenerate and are eventually replaced with adipose tissue and fibrous connective tissue (see Fig. 2 and Fig. 3).
The Duchenne gene has been located on the short arm of the X chromosome. This means that Duchenne is inherited as an X-linked recessive dise.... |
| Number of words: 1991 |
Approximate pages: 8 |
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