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The Cystic Fibrosis Gene

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Introduction: Cystic fibrosis is an inherited autosomal recessive disease that exerts its main effects on the digestive system and the lungs. This disease is the most common genetic disorder among Caucasians. Cystic fibrosis affects about one in 2,500 people, with one in twenty five being a heteroz ....

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....gth Polymorphism or RFLP for short. RFLP's are varying base sequences of DNA in different individuals which are known to travel with genetic disorders.3 The RFLP for cystic fibrosis was discovered through the techniques of Somatic Cell Hybridization and through Southern Blot Electrophoresis (gel separation of DNA). By using these techniques, three RFLP's were discovered for CF; Doc RI, J3.11, and Met. Utilizing in situhybridization, scientists discovered the CF gene to be located on the long arm....
Number of words: 2159 Approximate pages: 8

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