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Michael Smith Biography
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Smith, Michael (1932- ), British-born Canadian biochemist and Nobel Prize winner. Smith developed a method for altering the nucleic acid deoxyribonucleic acid (DNA) structure of protein molecules. His technique enabled scientists to determine with great accuracy the function of proteins in specific ....
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.... because viruses transmit their genetic code into bacterial cells when they are inserted into a bacterium. The bacteria then multiply, duplicating the gene. First, Smith spliced a normal gene into a single strand of viral DNA. He then created a complementary segment of DNA, but altered one specific coding site with a mutagen. He called this technique site-specific mutagenesis. The mutated segment then bonded to the normal gene, creating a double-stranded DNA structure. When this was inserted int.... |
| Number of words: 437 |
Approximate pages: 2 |
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